There is little evidence to back omega-3 fatty acids as a depression treatment

Reported by Susan Aldridge, PhD, medical journalist

Review shows that omega-3 fatty acids on their own are unlikely to cure depression.
Omega-3 fatty acids are found in fish oils and seem to have a protective effect against heart disease. It has also been suggested that they may be effective against depression by changing mood and behavior. The omega-3s could work like this, as they affect blood vessel activity in the brain. However, a new review suggests there is, as yet, little hard evidence to support the use of omega-3 supplements for depression.

The review, in Drugs and Therapeutic Bulletin, looks at how omega-3s perform both on their own and in conjunction with antidepressants. There was some limited evidence that they may be effective in depression when given with antidepressant medication. On their own, they do not seem sufficient. However, they are well-tolerated, although some supplements may contain environmental toxins, especially if they are made from fish liver. Omega-3s can also be obtained from oily fish, nuts, seeds and leafy green vegetables.

Source
Drug and Therapeutics Bulletin February 2007

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