12/23/2009 - Questions and Answers
I am looking for information on viscosupplementation with Hyalgan or Synvisc in treatment of osteoarthritis of the hip.
By: Mark Castleden
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I am looking for information on viscosupplementation with Hyalgan or Synvisc in treatment of osteoarthritis of the hip.
Answer
Synvisc is biologically similar to hyaluronan, which is a component of synovial fluid and responsible for its visco-elasticity. The indications for usage, according to the company, are as a temporary replacement and supplement for synovial fluid, as a treatment for patients in all stages of joint pathology (it is claimed to be most effective in those who are actively and regularly using the affected joint), and to treat pain associated with osteoarthritis of the knee. It should not be used if there is evidence of venous or lymphatic stasis in the leg or there is evidence of inflamed joints.
A Canadian multicentre trial comparing Synvisc, Synvisc with non-steroidal anti-inflammatory drugs and non-steroidal anti-inflammatory drugs alone was reported in Osteoarthritis and Cartilage 1995.3:213-226. The study was carried out in 102 sufferers with osteoarthritis of the knee. At 12 weeks, all groups were better, but there was no difference between the 3 groups. At 26 weeks, both groups receiving Synvisc were significantly better than the group receiving non-steroidal anti-inflammatory drugs alone. It was concluded that Synvisc was a safe and effective treatment for osteoathritis of the knee and could be used either as a replacement for, or an adjunct to, non-steroidal anti-inflammatory therapy.
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Created on: 06/12/2000
Reviewed on: 12/23/2009
Reviewed on: 12/23/2009
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Hi there
I'm an orthopaedic and sports med doctor based in Scotland. I've got extensive experience of using both synvisc and other similar products for osteoarthritis - mostly in the knee but also to a lesser extent in the hip. There's no doubt that Synvisc works but for injection into the hip the procedure is technically complex and needs x-ray imaging to guide the needle. Hope that helps.
You can read more about it on my site:
(this comment was moderated by the admin)
DR, DOES A SIGLE INJECTION OF SYNVISC-ONE,WORK AS GOOD AS THE 3 INJECTION PROCEDURE-RAY