If you are currently being treated with any of the following medications, you should not use chondroitin without first talking to your healthcare provider.

Blood-thinning Medications

Chondroitin and heparin, a drug used to thin the blood, are similar in chemical composition. For this reason, some researchers speculate that people may suffer bleeding complications from chondroitin, particularly when it is used in combination with other blood-thinning medications, such as warfarin or heparin.

Cisplatin

Preliminary animal studies also suggest that chondroitin sulfate may reduce the kidney toxicity associated with cisplatin, a chemotherapy drug used for cancer treatment. Further studies are needed to determine whether chondroitin has the same effect in people taking cisplatin.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Taking chondroitin supplements may result in a decreased need for NSAIDs such as ibuprofen to relieve the pain and swelling associated with OA. Because NSAIDs and aspirin can cause serious side effects, such as stomach bleeding and ulcers, chondroitin may be a useful adjunct or even alternative. Be sure to consult your healthcare provider before adding chondroitin to your healthcare regimen.