If you are currently being treated with any of the following medications, you should not use EPO without first talking to your healthcare provider.

Ceftazidime, an antibiotic
GLA from EPO or other sources may increase the effectiveness of ceftazidime, an antibiotic in a class known as cephalosporins, against a variety of bacterial infections.

Chemotherapy for cancer
GLA from EPO or other sources may increase the effects of anti-cancer treatments, such as doxorubicin, cisplatin, carboplatin, idarubicin, mitoxantrone, tamoxifen, vincristine, and vinblastine.

Cyclosporine
In animal studies, EPO administered during treatment with cyclosporine, a medication used to suppress immune function after an organ transplant, for example, may protect against kidney damage (a possible side effect of the medication).

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
Theoretically, use of NSAIDs, such as ibuprofen, together with borage oil or other GLA containing supplements like EPO may counter-act the effects of the supplement. Research in this area is needed to know if this theory is accurate.

Phenothizines for Schizophrenia
Individuals taking a class of medications called phenothiazines (such as chlorpromazine, fluphenazine, perphenazine, promazine, and thioridazine) to treat schizophrenia should not take EPO because it may interact with these medications and increase the risk of seizures.