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Table of Contents > Drugs >  Zidovudine
Zidovudine
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(zye DOE vyoo deen)

Brand Names
Retrovir®

Foreign Brand Names
Apo-Zidovudine® (Canada); Dipedyne (Mexico); Kenamil (Mexico); Novo-AZT (Canada); Retrovir-AZT (Mexico)

Therapeutic Categories
Antiretroviral Agent, Reverse Transcriptase Inhibitor (Nucleoside)

What key warnings should I know about before taking this medicine?

  • This medicine may cause severe changes in the number of blood cells, decreasing the ability to fight infections or causing symptoms of weakness and fatigue. This medicine may cause severe damage to the liver or a change in acid levels in the blood. This medicine may cause muscle aches and stiffness if it is used for long periods of time. Closely review the section in this leaflet which lists when to immediately call your healthcare provider.


Reasons not to take this medicine

  • If you have an allergy to zidovudine or any other part of the medicine.


What is this medicine used for?

  • This medicine is used to treat HIV infection. It is usually taken with 2 other medicines.


How does it work?

  • Zidovudine stops the HIV virus from increasing. It blocks reproduction of the virus.


How is it best taken?

  • The medicine must be taken exactly as directed.
  • Take on an empty stomach. Take 1 hour before or 2 hours after meals.
  • Avoid a high fat meal after taking this medicine.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop taking medicine without talking with healthcare provider.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Do not run out of this medication. Get it refilled today!
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Protect against sexual spread of disease. Use an effective method of birth control. Talk with healthcare provider if you have questions.
  • Can be used in pregnancy (helps decrease baby's risk of getting HIV disease).
  • Breast-feeding is not recommended in HIV disease.


What are the common side effects of this medicine?

  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Headache.
  • Anemia and low white blood cell count (can get infections easier).
  • Fever.
  • Rash.
  • Weakness.
  • No appetite.


What should I monitor?

  • Check blood work. Talk with healthcare provider.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Severe nausea, vomiting, and/or diarrhea.
  • Shortness of breath or decreased ability to exercise.
  • Belly pain, feeling tired, dark urine, yellow eyes/skin, not hungry.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved

 
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The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

  
  

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