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Table of Contents > Drugs >  Sodium Oxybate
Sodium Oxybate
Pronunciation
Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(SOW dee um ox i BATE)

Brand Names
Xyrem®

Therapeutic Categories
Central Nervous System Depressant

What key warnings should I know about before taking this medicine?

This medicine may be habit-forming. Make sure that you understand this medicine, what it is used for, how to use it, and when to go back to healthcare provider.


Reasons not to take this medicine
  • Do not give this medicine to a child younger than 16 years of age.
  • If you have an allergy to sodium oxybate or any other part of this medicine.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • If you have succinic semialdehyde dehydrogenase deficiency.
  • If you are on a low-salt or salt-free diet.
  • If you are breast-feeding.

  • What is this medicine used for?
  • This medicine is used to treat cataplexy (sudden emotional shock with loss of muscle tone) in patients with narcolepsy.

  • How does it work?
  • Sodium oxybate helps to decrease weakness.

  • How is it best taken?
  • Take this medicine on an empty stomach.
  • Keep the same amount of time between the last food of the day and the first dose.
  • Take two doses each night.
  • Take this medicine at a similar time every night.
  • Prepare each dose before going to bed.
  • Mix liquid with 1/4 cup of water.
  • Place in child-resistant dosing cups on bedside table.
  • Take first dose at bedtime after getting into bed.
  • Separate doses by at least 21/2 to 4 hours.
  • Set alarm clock to wake up for second dose.
  • Stay in bed after taking doses.

  • What do I do if I miss a dose?
  • If you miss the second dose, skip the missed dose and return to your regular schedule.
  • Do not take a double dose or extra doses.
  • Do not change dose or stop medicine. Talk with healthcare provider.

  • What are the precautions when taking this medicine?
  • Avoid alcohol (includes wine, beer, and liquor) or other medicines and natural products that slow your actions and reactions. These include sedatives, tranquilizers, mood stabilizers, antihistamines, and pain medicine.
  • You may not be alert. Do not drive a car, operate heavy machinery, or perform any activity that is dangerous or that requires mental alertness for at least 6 hours after taking.
  • This medicine may be habit-forming with long-term use.
  • If you have drug or alcohol addiction, talk with healthcare provider.
  • If you have mental illness or thoughts of suicide, talk with healthcare provider.
  • If you have liver disease, talk with healthcare provider.
  • If you have lung disease, talk with healthcare provider.
  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • are pregnant or plan on getting pregnant.

  • What are the common side effects of this medicine?
  • Feeling lightheaded, sleepy, having blurred vision, or a change in thinking clearly. Avoid driving, doing other tasks or activities that require you to be alert until you see how this medicine affects you.
  • Feeling dizzy. Rise slowly over several minutes from sitting or lying position. Be careful climbing.
  • Headache. Mild pain medicine may help.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Bedwetting.

  • What should I monitor?
  • Change in condition being treated. Is it better, worse, or about the same?
  • Follow up with healthcare provider.

  • Reasons to call healthcare provider immediately
  • If you suspect an overdose, call your local poison control center immediately or dial 911.
  • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
  • Sleepwalking.
  • Difficulty breathing.
  • Feeling extremely tired or weak.
  • Significant change in thinking clearly and logically.
  • Signs or symptoms of depression, suicidal thoughts, nervousness, emotional ups and downs, abnormal thinking, anxiety, or lack of interest in life.
  • Severe nausea or vomiting.
  • Any rash.
  • No improvement in condition or feeling worse.

  • How should I store this medicine?
  • Store in original container at room temperature.

  • General statements
  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.
  • Read the package insert for more details.

  • Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved

     
    The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

      
      

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