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| Pronunciation |
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(roe
si GLI ta
zone) |

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| Brand Names |
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| Avandia® |

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| Therapeutic
Categories |
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Antidiabetic Agent (Thiazolidinedione) |

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| Reasons not to take this
medicine |
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- If you have an allergy to rosiglitazone or any other part of the
medicine.
- If you have active liver disease or yellowing (jaundice) during
troglitazone therapy.
- If you have type 1 diabetes or an acid condition of the blood called
diabetic ketoacidosis.
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| What is this medicine used
for? |
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- This medicine lowers blood sugar in type 2 diabetics. It can be used
alone or in combination with other diabetes medicine. It may take up to 3 months
to see the full effect.
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| How does it work? |
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- Rosiglitazone increases insulin activity in the
body.
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| How is it best taken? |
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- Take with or without food. Take with food if this medicine causes an
upset stomach.
- Take at a similar time every day.
- Follow diet plan and exercise program as recommended by healthcare
provider.
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| What do I do if I miss a
dose? |
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- Take a missed dose as soon as possible.
- If it is missed at the usual meal, take it with the next meal.
- Do not take a double dose or extra
doses.
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| What are the precautions when
taking this
medicine? |
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- Wear disease medical alert identification for diabetes.
- Do not use if you have liver disease. Talk with healthcare provider.
- Use caution if you have high cholesterol (increases bad cholesterol).
Talk with healthcare provider.
- Use caution if you have a weakened heart. May cause water weight gain.
Talk with healthcare provider.
- During times of stress such as infection, trauma, or surgery your
medicine requirements may change. Talk with healthcare provider.
- Tell healthcare provider if you are allergic to any medicine. Make
sure to tell about the allergy and how it affected you. This includes telling
about rash; hives; itching; shortness of breath; wheezing; cough; swelling of
face, lips, tongue, throat; or any other symptoms involved.
- This medicine can cause ovulation in premenopausal women who have not
been ovulating. Birth control may need to be considered. Pregnancy can occur.
- Tell healthcare provider if you are pregnant or plan on getting
pregnant.
- Tell healthcare provider if you are
breast-feeding.
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| What are the common side effects
of this
medicine? |
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- Weight gain caused by swelling.
- Increased cholesterol (increase of 10% to 15%).
- Cough, cold, redness and swelling of the sinuses.
- Headache.
- Back pain.
- Rare, but serious liver
injury.
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| What should I monitor? |
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- Check blood sugar as ordered by healthcare provider. Call if glucose
is less than 80 mg/dL or greater than 250 mg/dL. Bring results to follow-up
visits.
- Watch for low blood sugar. This can cause anger, shaking, rapid
heartbeats, confusion, sweating.
- Watch for high blood sugar. Causes many trips to the bathroom, thirst,
and weight loss.
- Check blood work. Talk with healthcare provider.
- Follow diet plan and exercise program as recommended by healthcare
provider.
- Have an eye exam and visit to the foot doctor every year.
- Liver function tests need monitoring before therapy and then every 2
months for the first year and periodically after that. Talk with healthcare
provider.
- Check lipid (cholesterol) panel. Talk with healthcare
provider.
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| Reasons to call healthcare
provider
immediately |
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- Signs of a life-threatening reaction. These include wheezing;
tightness in the chest; fever; itching; bad cough; blue skin color; fits;
swelling of face, lips, tongue, or throat.
- Low blood sugar or very high blood sugar.
- Nausea, vomiting, belly pain, feeling tired, dark urine, yellow
eyes/skin, not hungry.
- For women, a change in monthly period.
- Any rash.
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| How should I store this
medicine? |
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- Store in a tight container at room
temperature.
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| General statements |
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- Do not share your medicine with others and do not take anyone else's
medicine.
- Keep all medicine out of the reach of children and pets.
- Keep a list of all your medicines (prescription, herbal/supplements,
vitamins, over-the-counter) with you. Give this list to healthcare provider
(doctor, nurse, pharmacist, physician assistant).
- Talk with healthcare provider before starting any new medicine,
including over-the-counter or natural products (herbs,
vitamins).
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Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved
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The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.
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