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Table of Contents > Drugs >  Mesalamine
Mesalamine
Pronunciation
Brand Names
Therapeutic Categories
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(me SAL a meen)

Brand Names
Asacol®; Canasa®; Pentasa®; Rowasa®

Therapeutic Categories
5-Aminosalicylic Acid Derivative

Reasons not to take this medicine

  • If you have an allergy to sulfasalazine, sulfites, aspirin or another salicylate, mesalamine, or any other part of the medicine.


What is this medicine used for?

  • This medicine is used for the treatment of ulcerative colitis.
  • The capsule or tablet is used for mild to moderately active ulcerative colitis.
  • The rectal forms (suppository, suspension) are used mild to moderate disease at the far end of the colon where they can reach.


How does it work?

  • Mesalamine works to decrease the irritation and inflammation caused by the ulcerative colitis.


How is it best taken?

  • Swallow tablet or capsule whole. Do not chew, break, or crush. Take with a whole glass of water.
  • Use suppository or suspension rectally only.
  • Shake suspension well first. Use at bedtime.
  • Keep suspension in rectum as long as possible.
  • Take foil off rectal suppository and insert pointed end first. Do not handle too much. It will melt in your hand.
  • You could be on both a tablet or capsule and a rectal form at the same time. Talk with healthcare provider.
  • Take entire prescription as directed, even if feeling better.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • The rectal suspension can stain clothing, other fabrics, flooring, painted surfaces, marble, granite, vinyl, and enamel. Be careful where you give yourself this medicine.
  • If you are 65 or older, you may have more side effects.
  • Tell healthcare provider if you are on warfarin.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Do not use if you are breast-feeding.


What are the common side effects of this medicine?

  • Belly pain and cramps.
  • Headache. Mild pain medicine may help.
  • Belching or burping.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea or constipation.
  • Rarely, liver problems.


What should I monitor?

  • Check kidney function before starting. The dose is adjusted to your kidney function.
  • Follow up with healthcare provider.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • If you see tablet bits in the stool.
  • Cramping, belly pain, or bloody diarrhea.
  • Fever.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight container at room temperature.
  • Keep rectal suspension in foil until ready to use. If rectal suspension is dark brown, throw away.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved

 
The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

  
  

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