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Table of Contents > Drugs >  Itraconazole
Itraconazole
Pronunciation
Brand Names
Foreign Brand Names
Therapeutic Categories
What key warnings should I know about before taking this medicine?
Reasons not to take this medicine
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(i tra KOE na zole)

Brand Names
Sporanox®

Foreign Brand Names
Isox (Mexico); Itranax® (Mexico)

Therapeutic Categories
Antifungal Agent, Oral

What key warnings should I know about before taking this medicine?

  • This medicine does not mix well with many medications. It should not be taken if you are also taking terfenadine, astemizole, and cisapride. Life-threatening reactions may occur. Check all medicines with healthcare provider.


Reasons not to take this medicine

  • If you have an allergy to another azole fungus medicine, itraconazole, or any other part of the medicine.
  • If you are taking any of these medicines: Astemizole, cisapride, lovastatin, midazolam, simvastatin, or triazolam.


What is this medicine used for?

  • This medicine is used for the treatment of certain types of fungus (yeast) infections. It can treat oral, esophageal (swallowing tube) infections and fingernail infections too.
  • Sometimes it is used to prevent fungus (yeast) infections.


How does it work?

  • Itraconazole causes a leakiness in the fungus (yeast) cell that causes its death.


How is it best taken?

  • To gain the most benefit, do not miss doses.
  • Take capsule with a full meal.
  • Do not take antacids or sucralfate within 2 hours of this medicine.
  • A liquid (solution) is available if you cannot swallow pills. Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after medicine is given.
  • Take liquid (solution) on an empty stomach. Take 1 hour before or 2 hours after meals.
  • Use entire prescription as directed, even if feeling better.
  • Avoid grapefruit and grapefruit juice.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • Do not take a double dose or extra doses.


What are the precautions when taking this medicine?

  • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
  • Avoid alcohol (includes wine, beer, and liquor). Can make infection more difficult to treat.
  • Limit caffeine (for example, tea, coffee, cola) and chocolate intake. Use with this medicine may cause nervousness, shakiness, rapid heartbeats, and anxiety.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Belly pain and cramps.
  • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard candy, or chewing gum may help.
  • Diarrhea. Call healthcare provider if severe or prolonged.
  • Headache. Mild pain medicine may help.
  • Rash. Talk with healthcare provider if one develops.


What should I monitor?

  • Watch for change in temperature or worsening of infection.


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Fever and/or chills, nausea, vomiting, belly pain, feeling tired, dark urine, yellow eyes/skin, no appetite.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight light-resistant container at room temperature. Protect capsules from moisture.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


Copyright © 1978-2001 Lexi-Comp Inc. All Rights Reserved

 
The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

  
  

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