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Table of Contents > Drugs >  Acetaminophen and Pseudoephedrine
Acetaminophen and Pseudoephedrine
Pronunciation
Brand Names
Therapeutic Categories
What is this medicine used for?
How does it work?
How is it best taken?
What do I do if I miss a dose?
What are the precautions when taking this medicine?
What are the common side effects of this medicine?
What should I monitor?
Reasons to call healthcare provider immediately
How should I store this medicine?
General statements

Pronunciation
(a seet a MIN oh fen & soo doe e FED rin)

Brand Names
Alka-Seltzer Plus® Cold and Sinus [OTC]; Allerest® No Drowsiness [OTC]; Children's Tylenol® Sinus [OTC]; Coldrine®[OTC]; Dristan® Cold [OTC]; Ornex®[OTC]; Ornex® Maximum Strength [OTC]; Sine-Aid® Maximum Strength [OTC]; Sine-Off® Maximum Strength No Drowsiness Formula [OTC]; Sinus-Relief®[OTC]; Sinutab® Sinus Maximum Strength Without Drowsiness [OTC]; Tavist® Sinus [OTC]; Tylenol® Sinus Maximum Strength [OTC]

Therapeutic Categories
Alpha/Beta Agonist; Analgesic, Miscellaneous

What is this medicine used for?

  • Acetaminophen is used to decrease pain.
  • Pseudoephedrine is used to dry up nasal stuffiness.


How does it work?

  • Acetaminophen decreases the production of chemicals called prostaglandins. This decreases pain.
  • Pseudoephedrine shrinks swollen nasal tissue and opens up passages. This increases sinus drainage.


How is it best taken?

  • Do not take more than prescribed amount. Liver damage can occur.
  • Make sure you are drinking enough liquids unless told to drink less by healthcare provider. Avoid products with caffeine.


What do I do if I miss a dose?

  • Take a missed dose as soon as possible.
  • If it is almost time for the next dose, skip the missed one. Return to your regular schedule.
  • This medicine may also be taken on an as needed basis depending on relief of symptoms, duration of cold, or allergy.


What are the precautions when taking this medicine?

  • Limit caffeine (for example, tea, coffee, cola) and chocolate intake. Use with this medicine may cause nervousness, shakiness, rapid heartbeats, and anxiety.
  • Pseudoephedrine can cause inability to sleep or nervousness.
  • Not for coughs due to smoking, asthma, or chronic obstructive pulmonary disease.
  • Use caution if you have high blood pressure. Talk with healthcare provider.
  • Tell healthcare provider if you are a heavy drinker. This medicine mixed with alcohol can cause liver damage.
  • Do not use over-the-counter products that increase blood pressure. These include cough or cold remedies, diet pills, stimulants, ibuprofen or like products, and certain herbs or supplements. Talk with healthcare provider.
  • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
  • Tell healthcare provider if you are pregnant or plan on getting pregnant.
  • Tell healthcare provider if you are breast-feeding.


What are the common side effects of this medicine?

  • Inability to sleep.
  • Very nervous and excitable.
  • Dry mouth. Frequent mouth care, sucking hard candy, or chewing gum may help.


What should I monitor?

  • Watch for change in symptoms. Is condition better, worse, or about the same?


Reasons to call healthcare provider immediately

  • Signs of a life-threatening reaction. These include wheezing; tightness in the chest; fever; itching; bad cough; blue skin color; fits; swelling of face, lips, tongue, or throat.
  • Cough continues for more than 1 week or tends to return.
  • Severe headache.
  • Any rash.
  • No improvement in condition or feeling worse.


How should I store this medicine?

  • Store in a tight, light-resistant container at room temperature.


General statements

  • Do not share your medicine with others and do not take anyone else's medicine.
  • Keep all medicine out of the reach of children and pets.
  • Keep a list of all your medicines (prescription, herbal/supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, pharmacist, physician assistant).
  • Talk with healthcare provider before starting any new medicine, including over-the-counter or natural products (herbs, vitamins).


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The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. No claims or endorsements are made for any drugs or compounds currently marketed or in investigative use. This material is not intended as a guide to self-medication. The reader is advised to discuss the information provided here with a doctor, pharmacist, nurse, or other authorized healthcare practitioner and to check product information (including package inserts) regarding dosage, precautions, warnings, interactions, and contraindications before administering any drug, herb, or supplement discussed herein.

  
  

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