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J.-L. THOMAS, B.T. QUANG, E. OCHSENBEIN, J.-P. VINCENT
Service de Gérontologie, Centre Hospitalier Emile Roux, Limeil
Brevannes (France). Correspondence: J.P. VINCENT, Centre Hospitalier Emile
Roux, 1 avenue de Verdun, F94556 Limeil Brevannes Cedex. Fax: +33 1 45
95 82 80. Email: isabelle.gentilhomme@erx.ap-hop-paris.fr
Abstract: BACKGROUND: The decrease in circulating testosterone levels
with advancing age has been shown to be related to biological changes
in healthy men. OBJECTIVE: We investigated the relationship between total
testosterone and several laboratory blood tests (glucose, total cholesterol,
total proteins, albumin, RBC) in elderly institutionalized men (mean age:
82.7 years) with chronic illness. RESULTS: There was a dramatically low
level of total testosterone in the sample and a strongly significant inverse
correlation between testosterone and fasting blood glucose. Hematocrit
and albumin were positively correlated to testosterone. CONCLUSION: The
negative correlation between testosterone and fasting blood glucose observed
in healthy men also exists in institutionalized subjects. The link between
testosterone and the related other biological parameters is questioned.
Key words: Aging, institutionalized men, testosterone, plasma glucose,
hematocrit, albumin.
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