Adult stem cells are found in mature humans and animals. They are cells
that have not themselves become specialized-but have the capacity to do
so. And new research suggests that they might have the capacity to mature
into almost any cell type the body might need.
Scientists in Sweden announced the results of experiments using adult
mouse stem cells. Such cells were taken from the brains of mature mice
and transplanted into both mouse and chicken embryos. The stem cells matured
into a variety of cell types-including beating heart cells.
Earlier research at other institutions, including Harvard, had clearly
demonstrated that nerve stem cells of mice could mature into needed specialized
nerve cells. Blood stem cells could mature into needed specialized blood
cells, but the Swedish experiments were the first to show that neural
stem cells could mature into a variety of needed specialized cells.
Scientists are cautiously optimistic as these experiments are the first
evidence that stem cells can be prodded to become virtually any needed
mature cell. Among the diseases they speculate we might eventually treat
with stem cell transplants are Parkinson's disease, Alzheimer's disease,
macular degeneration, stroke, type 1 diabetes, and spinal cord injuries.
Could the next generation see the clock turned back, and the diseases
of aging treated by stem cell transplant? Could repeated stem cell transplants
serve as a virtual fountain of youth, replacing tissues worn and damaged
by age? Only additional research will enable us to know if this staggering
promise can be realized.
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