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References
 


1- Abrams WB, Beers MH, Berkow R, eds. The Merck Manual of Geriatrics. 1995; New Jersey: Merck Research Laboratories.

2- Bjorksten J, Tenhu H. The crosslinking theory of aging--added evidence. Exp Gerontol 1990; 25L 91-5.

3- Hayflick, op cit.

4- Subba Rao K, Loeb LA. DNA damage and repair in brain: relationship to aging. Mutat Res 1992: 275: 317-29.

5- Harman D. Free radical theory of aging: history. EXS 1992; 62: 1-10.

6- Kalous M, Drahota Z. The role of mitochondria in aging. Physiol Res 1996; 45: 351-9.

7-Sastre J, Pallardo FV, Garcia de la Ascuncion J, Vina J. Mitochondria, oxidative stress and aging. Free Radic Res 2000; 32: 189-98.

8- Hayflick, op cit.

9- de Grey AD. A proposed refinement of the mitochondrial free radical theory of aging. Bioessays 1997; 19: 161-6.

10- Wei YH. Oxidative stress and mitochondrial DNA mutations in human aging. Proc Soc Exp Biol Med 1998; 217: 53-63.

11- Rustin P, von Kleist-Retzow J, Vajo Z, Rotig A, Munnich A. For debate: defective mitochondria, free radicals, cells death, aging-reality or myth-ochondria? Mech Ageing Dev 2000; 114: 210-6.

12- Greenberg JA. Organ metabolic rates and aging: two hypotheses. Med Hypotheses 1999; 52: 15-22.

13- "In search of the secrets of aging."

14- Fabris N. Biomarkers of aging in the neuroendocrine-immune domain. Time for a new theory of aging? Ann NY Acad Sci 1992; 663: 335-48.

15- Goldstein S, Gallo JJ, Reichel W. Biologic theories of aging. Am Fam Physician 1989; 40: 195-2000.

16- Barzilai N, Shuldiner A. Searching for human longevity genes: the future of gerontology in a post-genomic era. In press.

17- Graeber MB, Grasbon-Frodl E, Eitzen UV, Kosel S. Neurodegeneration and aging: role of the second genome. J Neurosci Res 1998; 52: 1-6.

18- Martin GM. Genetics and the pathology of ageing. Philos Trans R Soc Lond B Biol Sci 1997; 352: 1773-80.

 

 
 
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