Excess Abdominal Fat is Major Contributor to Inflammation

07/23/2009 - News

Excess Abdominal Fat is Major Contributor to Inflammation

By: June Chen, MD

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The same research group that showed cardiorespiratory fitness was inversely related to abdominal fat now reports that poor fitness in overweight and obese people is associated with low-grade inflammation.

In addition, they report that the relationship between obesity and inflammation is primarily attributable to the accumulation of abdominal fat rather than to overall excess body weight. These findings are published in the July 15, 2009 issue of the American Journal of Cardiology.

Investigators from the Université Laval in Quebec, Canada and their colleagues studied a group of 272 non-diabetic men and women and scored them for inflammation based on plasma biomarker levels. They also measured abdominal fat using computed tomography (CT). The investigators found that increased abdominal fat was associated with increased levels of C-reactive protein (CRP) and interleukin-6, both markers for inflammation.
 
The level of abdominal fat varies widely, even among individuals with the same body mass index (BMI). In this study, inflammation scores were reduced in study participants with low levels of belly fat. From their findings, the investigators concluded that there may be a link between low cardiorespiratory fitness and low-grade inflammation and an associated insulin-resistant state.
 

Source:

Am J Cardiol. 2009;104:240-246.

Created on: 07/18/2009
Reviewed on: 07/23/2009

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