A new study shows that we have a gene which helps protect the heart from the effects of stress.

Earlier research has shown that some people respond to the stress of everyday life more than others. Eventually, the wear and tear stress wreaks on the nervous system may lead to heart disease. Mayo Clinic researchers have now uncovered a gene, known as Kir6.2, which helps mediate the stress response.

Mice which had had their Kir6.2 gene 'knocked out' were very vulnerable to stress. When they were given a treadmill test, three quarter of them died from a fatal heart rhythm. The normal mice suffered no ill effects. It's known that Kir6.2 is present in all animals, including humans. Further research may reveal how Kir6.2 protects the heart from stress. Then it may be possible to boost its effects or repair any defects in the gene which may make certain people more vulnerable.

Source

Proceedings of the National Academy of Sciences 1st October 2002